Acetylation of Protein Amino Termini and 
the Side Chain of Lysine


Figure Text / Monograph 0003

Amino Acid Residue Composition

Residue Monoisotopic Mass

Delta Mass

Glycine (any AA) C2H4NO (+H) 58.0293 0
Acetyl-Glycine C4H6NO2 100.0399 42.0106

For each internal Lysine add 42.0106 u


Lysine and Glutamine have nearly isobaric mass, an acetylation of the Lysine side chain differentiates these two amino acids by 42 u.

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