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N-
and O-linked |
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"N-Linked " |
- |
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| All N-linked carbohydrates are
linked through N-Acetylglucosamine and the amino acid asparagine as
shown in Figure 1.
The N-linked amino acid consensus sequence is Asn-any AA- Ser or Thr. The middle amino acid can not be proline (Pro). |
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Figure 1 |
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- |
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"O-Linked " |
- |
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| Most O-linked carbohydrate
covalent attachments to proteins involve a linkage
between the monosaccharide N- Acetylgalactosamine and the amino
acids serine or threonine.
Currently there is not an O-linked amino acid consensus sequence.
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Figure 2 |
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