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Monograph 0004 
S-Carboxymethylation of Cysteine

Chemical Information Data Base

.Name
and
Description
Abbrev. Composition Structure Mono
Mass

Average
Mass

Dithiothreitol DTT

C4H10O2S2

154.01222

154.3
Iodoacetic Acid IAA

C2H3O2I

185.91778 186.0
Cysteine
AA Residue
Cys

C

C3H5NOS 103.00918 103.1

S-Carboxymethylated 
Cysteine Residue

CMC C5H7NO3S

161.01466

161.2

Additional Reducing and S-Carboxymethylation Agents

2-Mercaptoethanol
(reducing agent,  DTT is a stronger reducing agent )

BME

C2H6OS

78.01394 78.1

Tributylphosphine
(volatile reducing agent)

-

C12H27P

202.18504

202.3

4-Vinylpyridine
(alkylating agent)

-

C7H7N

105.05785

105.1

           

TOC     Introduction     Reaction     Method      Method Notes      Why Reduce?     RCM

Compound Data Base     Order Reagents      References      

     


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Last updated:  Tuesday, January 19, 2016 02:49:22 PM